ÁøÈ ¡í
¹æ»ç¼±, GMO ¡í
¹ß¾Ï¹°Áú
º¯ÀÌÀ¯±âÁ¦(mutagen)
¹ß¾Ï¿øÀÎ
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³ªÀÌ (º¹»ç ¿À·ù) :
¼³°è ¿À·ù,
¿îÀÌ ¾ø¾î¼
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IARC°øÀÎ :
3´ë ¹ß¾Ï¹°Áú ,
º¯ÀÌ¿ø
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½Ä»ç¿Í ¿îµ¿ :
õ¿¬½ÄÇ°,
ÀüÅë ½ÄÇ°
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Á÷¾÷ : ÈÇй°, ¸ÕÁö, ¾ß±Ù
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Á¶»ç : ¹æ»ç¼±, UV, ÀüÀÚÆÄ
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°¨¿° : ¹ÙÀÌ·¯½ºµµ ¹ß¾ÏÀÇ ¿øÀÎ
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È£¸£¸ó :
¼ºÀåÈ£¸£¸ó
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À¯Àü
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Nucleotide À¯ÀüÀÚÀÇ building block
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¹ß¾Ï¹°Áú
¡Ü DNAº¹»ç error´Â ±Ùº»ÀûÀÎ º¯ÀÌ¿øÀÌ´Ù
- Base analog, which can substitute for DNA bases and cause copying errors
¡Ü žçÀÇ X¼±, ¹æ»ç¼±Àº ÅÂ°í ºÎÅÍ ÀÖ¾ú´Ù
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UV »ì±Õ°°Àº º¯ÀÌ¿øÀº Áõ°¡ÇÏ¿´´Ù
- ¿°±â »çÀÌ¿¡ ³¢¾îµé¾î ¿°±â °£°ÝÀ» 3.4A¿¡¼ 6.8A·Î ¹Ù²Ù´Â acridine»ö¼Ò
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Alkylating agent : Purine, Pyrimidine ¿°±âÀÇ Áú¼Ò¸¦ alkylation
- Deaminating agents : Purine, Pyrimidine ÀܱâÀÇ Å»¾Æ¹Ì³ë
- Intercalating agents such as ethidium bromide
- Transposon, a section of DNA that undergoes autonomous fragment relocation/multiplication
- Alkaloid plants, such as those from Vinca species
- Bromine and some compounds that contain bromine in their chemical structure
- Sodium azide, an azide salt that is a common reagent in organic synthesis and a component in many car airbag systems
- Psoralen combined with ultraviolet radiation causes DNA cross-linking and hence chromosome breakage
- Benzene, an industrial solvent and precursor in the production of drugs, plastics, synthetic rubber and dyes