trans-4-tert-butylcyclohexanol is an antagonist of the heat receptor TRPV1 and thus is useful for reducung "heat sensations". See Kueper, T., Krohn, M., Haustedt, L. O., Hatt, H., Schmaus, G. and Vielhaber, G. (2010), Inhibition of TRPV1 for the treatment of sensitive skin. Experimental Dermatology, 19: 980-986.
Also can mitigate the hot sensations of capsaicin.
In WIPO Patent Application WO/2010/149798 (12/29/2010) by T. Kueper et al. trans-4-tert-Butylcyclohexanol is shown to be useful f ...