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The fermented fruit contains about 2% vanillin; in vanilla pods of good quality, the crystallised vanillin is visible on the surface. Although vanillin dominates the aroma, many other compounds do significantly improve the taste; among these are p-hydroxy-benzaldehyd (0.2%), p-hydroxybenzyl methyl ether, (0.02%) and about 130 more compounds (phenoles, phenol ether, alcohols, carbonyl compounds, acids, ester, lactones, aliphatic and aromatic carbon hydrates and heterocyclic compounds). Two stereoisomeric vitispiranes (2,10,10-trimethyl-1,6- and methylidene-1-oxaspiro(4,5)dec-7-ene), although only occurring in traces, also influence the aroma.

The quite different fragrance of Tahiti vanilla is due to its additional contents of piperonal (heliotropin, 3,4-dioxymethylenbenzaldehyd) and diacetyl (butandione).