식품 ≫ 기호성 ≫ 맛의 종류

6-TM : TRP 수용체의 진화 계통

TRP 수용체 :  수용체
- TRP 온도수용체 : TRPA1, TRPM8, TRPV4, TRPV3, TRPV1 :

 

 

TRP 온도수용체 : TRPA1, TRPM8, TRPV4, TRPV3, TRPV1 :
- TRPA1 차가운 통증 수용체, Gas 감각 O2, CO2
- TRPM8 시원함 (Cooling) : 멘톨
- TRPV4 온도수용체 :
- TRPV3 온도수용체 :
- TRPV1 뜨거운 통증 수용체


 





Transient receptor potential channels (TRP channels) are a group of ion channels located mostly on the plasma membrane of numerous animal cell types. There are about 30 TRP channels that share some structural similarity to each other.
Group 1 includes TRPC ( "C" for canonical), TRPV ("V" for vanilloid), TRPM ("M" for melastatin), TRPN ("N" for no mechanoreceptor potential C) , and TRPA ("A" for ankyrin).
group 2, there are TRPP ("P" for polycystic) and TRPML ("ML" for mucolipin).

Many of these channels mediate a variety of sensations such as pain, temperature, different kinds of tastes, pressure, and vision. In the body, some TRP channels are thought to behave like microscopic thermometers and used in animals to sense hot or cold.[2] Some TRP channels are activated by molecules found in spices like garlic (allicin), chili pepper (capsaicin), wasabi (allyl isothiocyanate); others are activated by menthol, camphor, peppermint, and cooling agents; yet others are activated by molecules found in cannabis (i.e., THC, CBD and CBN) or stevia. Some act as sensors of osmotic pressure, volume, stretch, and vibration.

These ion channels have a relatively non-selective permeability to cations, including sodium, calcium and magnesium.



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