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±Û¸®½Å Glycine

- Gluamic acid, glutamine
- Aspartic acid, asparagine
- serine, threonine,  glycine, valine
- alanine, leucine, isoleucine
- lysine, arginine, histidine, proline
- methionine, Cysteine
- Tyrosine, Phenylalanie, Tryptophan

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In higher eukaryotes, D-Aminolevulinic acid, the key precursor to porphyrins, is biosynthesized from glycine and succinyl-CoA. Glycine provides the central C2N subunit of all purines.[10]
  
Glycine is an inhibitory neurotransmitter in the central nervous system, especially in the spinal cord, brainstem, and retina. When glycine receptors are activated, chloride enters the neuron via ionotropic receptors, causing an Inhibitory postsynaptic potential (IPSP). Strychnine is a strong antagonist at ionotropic glycine receptors, whereas bicuculline is a weak one. Glycine is a required co-agonist along with glutamate for NMDA receptors. In contrast to the inhibitory role of glycine in the spinal cord, this behaviour is facilitated at the (NMDA) glutaminergic receptors which are excitatory.[citation needed] The LD50 of glycine is 7930 mg/kg in rats (oral),[12] and it usually causes death by hyperexcitability.

There is some evidence showing that 3000 milligrams of glycine before bedtime improves sleep quality

 

 


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